Meds That Treat Anxiety Anxiety is one of the most prevalent mental health problems which affects more than 40 million people in the United States. A variety of medications are available to treat anxiety. SSRIs (selective serotonin reuptake inhibitors) and SNRIs (serotonin-norepinephrine reuptake inhibitors), like Zoloft, Prozac, Lexapro and Effexor,